Trushar Patel


Published articles: 55, with first author of 21 articles and corresponding author of 17 articles. > 700 citations with an h-index of 15.

‘*’ and ‘#’ indicate shared authorship and corresponding authorship respectively

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  • Mrozowich, T, Winzor, D.J., Scott, D.J., and Patel, T.R. (2019) Use of molecular crowding for the detection of protein self-association by size-exclusion chromatography. Anal. Biochem. 10(584): 113392. DOI: 10.1016/j.ab.2019.113392
  • Gemmill, D., D'souza, S., Meier-Stephenson, V., and Patel, T.R. (2019) Current approaches for RNA labelling to identify RNA-binding proteins. Biochem. Cell Biol. In press. DOI: 10.1139/bcb-2019-0041 (IF: 2.250)
  • Ferens F.G., Patel, T.R., Oriss, G., Court, D.A., and Stetefeld, J. (2019) A Cholesterol Analog Induces an Oligomeric Reorganization of VDAC. Biophys. J. 116(5): 847-859. DOI: 10.1016/j.bpj.2019.01.031 (IF: 3.495)
  • Mrozowich, T., Meier-Stephenson, V., and Patel, T.R. (2019) Microscale thermophoresis: warming up to a new biomolecular interaction technique. The Biochemist 41(2): 8-13.


  • Mrozowich, T., McLennan, S., Overduin, M. and Patel, T. R.# (2018) Structural Studies of Macromolecules in Solution using Small Angle X-Ray Scattering. J. Vis. Exp. 141: e58538. DOI: 10.3791/58538  (IF: 1.232) 
  • Meier-Stephenson, V., Bremner, W.T.R., Dalton, C.S., van Marle, G., Coffin, C.S., and Patel, T.R.# (2018) Comprehensive Analysis of Hepatitis B Virus Promoter Region Mutations. Viruses 10: 603. DOI: 10.3390/v10110603. (IF: 3.76)
  • Byron, O., Nischang, I., and Patel, T.R. (2018) Analytical ultracentrifugation (AUC): a seminal tool offering multiple solutions. Eur. Biophys. J. 47(7): 693-696. DOI: 10.1007/s00249-018-1333-z. (IF: 1.935)
  • Kotb, A., Hyndman, E. and Patel, T. R.# (2018) The role of zyxin in regulation of malignancies. Heliyon4(7): e00695. DOI: 10.1016/j.heliyon.2018.e00695 (IF: N/A)
  • Meier, M.,  Moya-Torres, A., Krahn, N.J., McDougall, M.D., Orriss, G.L., McRae, E.K.S., Booy, E.P., McEleney, K., Patel, T.R., McKenna, S.A., and Stetefeld, J. (2018) Structure and hydrodynamics of a DNA G-quadruplex with a cytosine bulge. Nucleic Acids Res. 46(10): 5319-5331. DOI: 10.1093/nar/gky307 (IF: 11.56)
  • Isaac, C., Patel, T.R. and Zovoilios, A. (2018) Non-coding RNAs in Virology: an RNA Genomics Approach. Biotechnol. Genet. Eng. Rev. 34: 90-106. DOI: 10.1080/02648725.2018.1471642 (IF: 1.7) EditorsPatel, T.R., van Marle, G. and Mayes, S.
  • Dznanovic, E., McKenna, S. A. and Patel, T. R.# (2018) Viral Proteins Targeting Host Protein Kinase R to Evade an Innate Immune Response: A Mini Review. Biotechnol. Genet. Eng. Rev. 34: 33-59. DOI: 10.1080/02648725.2018.1467151 (IF: 1.7) EditorsPatel, T.R., van Marle, G. and Mayes, S.
  • Meier-Stephenson, V., Mrozowich, T., Pham, M. and Patel, T. R.# (2018) DEAD-box helicases: the Yin and Yang roles in viral infections. Biotechnol. Genet. Eng. Rev.  34: 3-32. DOI: 10.1080/02648725.2018.1467146 (IF: 1.7) EditorsPatel, T.R., van Marle, G. and Mayes, S.
  • van Marle, G., and Patel, T.R. (2018) Proceedings of the Alberta Virology Conference, University of Alberta, 1–2 June 2017; edited by Guido van Marle and Trushar R. Patel. Biotechnol. Genet. Eng. Rev. 34(1): 1-2. DOI: 10.1080/02648725.2018.1478662 (IF: 1.7) (editorial)
  • Patel, T. R.#, Besong, T. M., Meier, M., McEleney, K., Harding, S. E., Winzor, D. J. and Stetefeld, J. (2018) Interaction studies of a protein and carbohydrate system using an integrated approach: a case study of miniagrin – heparin system. European Biophysics Journal. In Press. DOI: 10.1007/s00249-018-1291-5 (IF: 1.935)


  • Krahn, N. Meier, M., To, V., Booy, E. P., McEleney, K., O’Neil, J. McKenna, S. A., Patel, T. R.# and Stetefeld, J. (2017) Nano-scale assembly of high-mobility group AT-hook 2a protein with DNA replication fork. Biophys. J. 113(12): 2609-2620. DOI: 10.1016/j.bpj.2017.10.026 (IF: 3.495)
  • Dzananovic, E., Astha., Chojnowski, G., Deo, S., Booy, E. P., McEleney, K., Bujnicki, J. M., Booy, E. P., Bujnicki, J. M., Patel, T. R.# and McKenna, S. A. (2017) Impact of the structural integrity of the three-way junction of adenovirus VAI RNA on PKR inhibition. PLoS One 12: e0186849, 1-21. DOI: 10.1371/journal.pone.0186849 (IF: 2.766)
  • Patel, T. R.#, Winzor, D. J. and Scott, D. J. (2017) Allowance for radial dilution in evaluating the concentration dependence of sedimentation coefficients for globular proteins. Eur. Biophys. J. In Press. DOI: 10.1007/s00249-017-1259-x (IF: 1.935)
  • Hyde, E. I., Callow, P., Rajesekar K. V., Timmins, P., Patel, T. R., Siligardi, G., Hussain, R., White, S. A., Thomas, C. M., and Scott, D. J. (2017) Intrinsic disorder in the partitioning protein KorB persists after cooperative complex formation with operator DNA and KorA. Biochem. J. 474: 3121-3135. DOI: 10.1042/BCJ20170281 (IF: 3.857)
  • Patel, T. R.#, Chojnowski, G., A., Koul, A., McKenna, S. A. and Bujnicki, J. M. (2017) Structural Studies of RNA-protein Complexes: A Hybrid Approach Involving Hydrodynamics, Scattering, and Computational Methods. Methods 118-119: 146-162. DOI: 10.1016/j.ymeth.2016.12.002 (IF: 3.998)
  • Krahn, N., Spearman, M, Meier, M., Spearman, M., Dorion-Thibaudeau, J., McDougall, M., Patel, T. R., De Crescenzo, G., Durocher, Y., Stetefeld, J. and Butler, M.  (2017) Inhibition of glycosylation on a camelid antibody uniquely affects its FcγRI binding activity. Eur. J. Pharm. Sci. 96: 428-39. DOI: 10.1016/j.ejps.2016.09.040 (IF: 3.466)


  • Reuten R.*, Patel, T. R.*, McDougall, M.*, Rama, N., Nikodemus, D., Gibert, B., Delcros, J., Prein, C., Meier, M., Metzger, S., Zhou, Z., Kaltenberg, J., McKee, K. K., Bald, T., Tüting, T., Zigrino, P., Djonov, V., Bloch, W, Clausen-Schaumann, H., Poschl, E., Yurchenco, P. D., Ehrba, M., Mehlen, P., Stetefeld, J. and Koch, M. (2016) Structural decoding of netrin-4 reveals a regulatory function towards mature basement membranes. Nat. Commun. 7: 13515. DOI: 10.1038/ncomms13515 (IF: 12.35)
  • Stetefeld, J., McKenna, S. A. and Patel, T. R.# (2016) Dynamic light scattering: A practical guide and applications in biomedical sciences. Biophys. Rev.: 1-19. DOI: 10.1007/s12551-016-0218-6
  • Gillis, R. B., Adams, G. G., Besong, T. M., Machová, E., Ebringerová, A., Rowe, A. J., Harding, S. E. and Patel, T. R.# (2016) Application of novel analytical ultracentrifuge analysis to solutions of fungal mannans. Eur. Biophys. J.:1-11. DOI: 10.1007/s00249-016-1159-5 (IF: 1.935)
  • Sarhan, A. R., Patel, T. R., Tomlinson, M. G., Hellberg, C., Heath, J. K., Cunningham, D. L. and Hotchin N. A. (2016) LAR protein tyrosine phosphatase regulates focal adhesions through CDK1. J. Cell Sci. 29: 175-85. DOI: 10.1242/jcs.191379 (IF: 4.401)
  • Sarhan, A. R., Patel, T. R., Creese, A. J., Tomlinson, M. G., Hellberg, C., Heath, J. K., Hotchin N. A. and Cunningham, D. L. (2016) Regulation of platelet derived growth factor signalling by Leukocyte common antigen-related (LAR) protein tyrosine phosphatase: a quantitative phosphoproteomics study. Mol. Cell. Proteomics 15: 1823-36. DOI: 10.1074/mcp.M115.053652 (IF: 5.322)
  • Reuten, R., Nikodemus, D., Oliveria, M. B., Patel, T. R., Brachvogel, B., Breloy, I., Stetefeld, J. and Koch, M. (2016) Maltose-binding protein (MBP), a secretion-enhancing tag for mammalian protein expression systems. PLoS One 1: e0152386. DOI: 10.1371/journal.pone.0152386 (IF: 2.766)
  • Grandin, M., Meier, M., Delcros, J, G., Nikodemus, D., Reuten, R., Patel, T. R., Goldschneider, D., Orriss, G., Krahn, N., Dean, Y., Neves, D., Bernet, A., Depil, S., Schneiders, F., Poole, K., Mehlen, P., Koch, M. and Stetefeld, J. (2016) Structural decoding of the Netrin-1/UNC5 interaction and its therapeutical implications in cancers. Cancer Cell 29: 175-85. DOI: 10.1016/j.ccell.2016.01.001 (IF: 22.82)
  • Patel, T. R.#, Nikodemus, D., Reuten, R., Besong, T. M., Meier, M., Winzor, D. J., Koch, M. and Stetefeld, J. (2016) Biophysical analysis of a lethal laminin alpha-1 mutation reveals altered self-interaction. Matrix Biol. 49: 93-105. DOI: 10.1016/j.matbio.2015.06.005 (IF: 8.136)
  • Patel, T. R.#, Winzor, D. J. and Scott, D. J. (2016) Analytical ultracentrifugation: A versatile tool for the characterisation of macromolecular complexes in solution. Methods 95: 55-61. DOI: 10.1016/j.ymeth.2015.11.006 (IF: 3.998)